Clinical Research & Guideline Archive
Explore all 42 clinical scenarios powering the Fiples simulation engine. Every decision is cross-referenced with guideline citations from the CDC, WHO, AHA, AAP, NIH, and USPSTF.
Crossing the Busy School Street
School just ended. Friends are darting across the street between parked SUVs to reach the ice cream truck without looking.
βNever step out between parked cars! Always use marked crosswalks and look both ways twice.β
Booster Seatbelt & Curbside Exit
The car pulls up to school. You want to unbuckle early while rolling and push the traffic-side door open quickly.
βAlways exit onto the sidewalk! Stay buckled until the car is completely in park.β
Post-Playground Handwashing Protocol
Lunch bell rings right after tag. Lines for the sink are long, and friends are sitting down to eat with dusty hands.
βSing the Happy Birthday song twice while scrubbing palms, backs of hands, and under fingernails!β
Bedtime Tooth Shielding
You had sweet dessert and are feeling sleepy in bed with your tablet.
βBrushing at night shields your teeth when your mouth produces less protective saliva.β
Cough & Sneeze Etiquette
You feel a sudden tickle and a big sneeze coming while sharing coloring crayons with your desk partner.
βUse the "Vampire Sneeze" into the crook of your elbow to keep hands germ-free!β
Playground Waste & Environmental Habit
After finishing your juice box and snack in the park, the trash bin is 30 steps away across the grass.
βKeep public parks clean! Always carry your wrappers to the recycling or waste bin.β
Peer Acute Asthma First Aid
During soccer practice, your teammate suddenly stops, clutching their chest, wheezing loudly and unable to speak in full sentences.
βNever make an asthma patient lie flat! Keep them upright, calm, and fetch the inhaler immediately.β
Residential Smoke & Fire Alarm Evacuation
Loud smoke detectors shriek in the middle of the night. Thin gray smoke is creeping under your bedroom door.
βGet low and go! Never hide in closets or under beds during a fire alarm.β
Pool & Open Water Safety
At a community lake party, older kids are daring everyone to jump off a murky dock where the depth is unknown.
βFeet first, first time! Always check water depth and never swim alone.β
UV Sunlight & Melanoma Shielding
It is a clear summer noon at the park. The sun is blazing and everyone wants to run to the splash pad without sunscreen.
βApply sunscreen 15 minutes before going outside and reapply every 2 hours after swimming!β
Hydration: Pure Water vs. Sugary Soda
After running in PE, the school cafeteria offers ice-cold water or 16oz sugary sodas loaded with 40g of high-fructose corn syrup.
βWater is the true champion drink for energy, clear thinking, and strong muscles!β
Childhood Immunization & Checkup
It is time for your back-to-school wellness visit. The nurse brings out your scheduled MMR and DTaP booster immunizations.
βA quick pinch today grants lifetime immunity against dangerous childhood contagions!β
Midnight Scrolling vs. Circadian Sleep
It is 11:30 PM. Endless short-form video notifications keep lighting up your smartphone.
βDock your phone across the room to unlock restorative deep REM sleep!β
Headphone Volume & Auditory Hair Cells
While gaming or listening to music, you notice your phone volume is at 100% (exceeding 100 decibels).
βUse the 60/60 rule: Never exceed 60% maximum volume, and take listening breaks every 60 minutes.β
High School Athletics & Thermoregulatory Hydration
During afternoon soccer practice in 88Β°F heat, you begin experiencing mild quadriceps twitches.
βDrink cool water and balanced electrolytes every 15-20 minutes during intense heat practice.β
Morning Fuel: High-Sugar Pastry vs. Protein & Complex Fiber
You have 10 minutes before the morning school bus arrives. Your kitchen has multiple breakfast options.
βPair eggs, Greek yogurt, or oatmeal with berries for steady sustained morning energy.β
Heavy Backpack Ergonomics & Spinal Alignment
Your backpack weighs 28 lbs with heavy textbooks and laptop. You are about to walk to school.
βKeep backpack weight under 10-15% of body weight and always wear both padded shoulder straps.β
Orthodontic Brackets & Interdental Plaque De-mineralization
You have dental braces and just finished dinner. Bedtime is approaching.
βUse a proxy brush, dental floss threader, and fluoride toothpaste twice daily.β
Midday Turf Sports & Broad Spectrum UV Defense
You are playing in a 4-hour weekend tennis tournament between 11:00 AM and 3:00 PM with UV index 9.
βApply SPF 30+ 15 minutes before sun exposure and reapply every 2 hours or immediately after sweating.β
High-Stimulant Energy Cans vs. Natural Fatigue Management
Studying for chemistry finals, you feel tired at 8:00 PM. A friend suggests slamming two 300mg caffeine "ultra" cans.
βTake a 20-minute power nap or brisk walk instead of megadosing synthetic caffeine stimulants.β
Acute Exam Panic & 4-7-8 Parasympathetic Vagal Reset
Sitting in the auditorium before the state SAT exam, your heart races to 130 bpm with cold, trembling hands.
βPractice 4-7-8 breathing: Inhale 4s, hold 7s, exhale slowly for 8s to calm the nervous system.β
Bedroom Thermal Environment & Sleep Depth Optimization
Your bedroom is heated to 76Β°F with bright hallway LED light creeping under the door.
βSet bedroom thermostat to 65β68Β°F and install blackout shades for uninterrupted cellular repair.β
Vaping Peer Pressure in Restroom
Between classes, friends in the restroom offer you a high-nicotine flavored e-cigarette cartridge.
βSaying NO protects your lung capacity, athletic VO2 max, and brain development.β
Social Media Comparison & Digital Detox
You notice feeling anxious and insecure after scrolling through hyper-curated influencer lifestyle feeds.
βMute accounts that trigger negative self-talk and replace passive scrolling with active creative hobbies.β
Lunch Choice: Whole Meal Prep vs. Fast Food
It is lunch hour. Friends are driving to the drive-thru for fried chicken tenders, large fries, and milkshakes.
βFuel up with grilled chicken, whole grains, and fresh fruits for sustained stamina and clear skin.β
HPV Cancer-Preventive Vaccination
At your adolescent wellness checkup, the pediatrician recommends the 9-valent HPV vaccine series.
βThe HPV vaccine is an actual cancer-preventing vaccine for lifetime oncology defense!β
Academic Overwhelm & Counseling Support
Exam stress and personal pressure have left you feeling exhausted, withdrawn, and unable to enjoy activities for over 3 weeks.
βAsking for support is a sign of strength! Talk to a school counselor, doctor, or trusted adult.β
Driver Distraction: Text Notification at 55 MPH
You are driving home on the highway at 55 MPH. Your phone chimes in your lap with an urgent group text.
βEnable "Do Not Disturb While Driving" mode and keep eyes locked on the road.β
Acute Cafeteria Anaphylaxis & Epinephrine Auto-Injector
A classmate with a known peanut allergy accidentally ingests peanut oil. Within 60 seconds, their lips swell, voice turns hoarse, and they begin wheezing severely.
βAdminister the EpiPen into the outer mid-thigh immediately, hold for 3 seconds, and call 911!β
Gymnasium Sudden Cardiac Arrest & Automated Defibrillation
During basketball practice, a player collapses face forward, becomes unresponsive, and has no pulse with agonal gasping.
βStart hard, fast chest compressions in center of chest, send someone for the AED, and call 911!β
Dining Hall Acute Airway Obstruction & Abdominal Thrusts
A friend laughing while eating suddenly clutches their neck (universal choking sign), cannot speak, and their face turns purplish-blue.
βStand behind victim, wrap arms around waist, place fist just above navel, and deliver quick upward thrusts.β
Helmet Collision & Concussion Return-to-Play Protocol
After a hard collision on the athletic field, you feel dizzy, sensitive to stadium lights, and have a throbbing headache.
βWhen in doubt, sit out! Report all concussion symptoms immediately and follow a graduated medical return protocol.β
Post-Party Transportation: Rideshare vs. Impaired Driving
You attended a celebratory networking dinner and consumed three alcoholic cocktails over two hours. Your car is parked outside.
βNever drive after drinking! Order a rideshare, call a sober friend, or take public transit.β
Desk Ergonomics & Sedentary Micro-Breaks
You have been seated at your computer for 4 continuous hours without standing or stretching during a deadline.
βStand up, stretch, and walk for 2 minutes every hour to counter sedentary sitting risks.β
Baseline Fasting Biomarkers (ApoB, HbA1c, Lipids)
You turned 25 and have not had a comprehensive medical checkup or fasting lipid profile in 4 years.
βSchedule routine annual wellness checkups with comprehensive lipid and fasting glucose panels.β
Barrier Protection & Routine STI Screening
Entering a new intimate relationship, discussions about sexual health and testing arise.
βUse barrier protection consistently and get routine STI screenings with new partners.β
Acute Workplace Anxiety & Physiological Sigh Protocol
Prior to delivering a high-stakes board presentation, your pulse spikes to 140 bpm with rapid, shallow chest breathing.
βTake a double inhale through the nose, followed by a long, slow sigh out the mouth.β
Flash Flood Roadway: "Turn Around, Donβt Drown"
Driving at night during a severe storm, you encounter 12 inches of murky moving water covering a low roadway bridge.
βNever drive through flooded roadways! Turn around and find an alternate elevated route.β
Wildfire Smoke Air Quality (AQI > 200) & Outdoor Exertion
Wildfire smoke blankets the city with an AQI of 215 (Very Unhealthy, PM2.5 > 150 ug/m3). You planned a 10-mile outdoor run.
βWhen AQI exceeds 150, move cardiovascular workouts indoors with HEPA air filtration or wear an N95 respirator outdoors.β
Acute Bacterial Gastroenteritis & Oral Rehydration Salts (ORS)
Six hours after eating undercooked poultry, you experience acute nausea, emesis, and watery diarrhea.
βSip WHO-standard Oral Rehydration Solution (ORS) or electrolyte broth slowly rather than plain water alone.β
Chronic Snoring, Morning Headaches & Sleep Apnea Screening
You wake up daily with dry mouth, morning frontal headaches, and severe 2:00 PM sleepiness despite 8 hours in bed.
βConsult a sleep specialist for home polysomnography if you snore loudly or wake up exhausted.β
Microbiome Health: Fermented Foods & Fiber vs. Ultra-Processed Diet
Planning weekly groceries: convenience aisles of packaged ultra-processed snacks vs fresh produce and fermented foods.
βTarget 30 grams of diverse dietary fiber and fermented foods daily (kefir, kimchi, sauerkraut, legumes).β
Milestone Age-45 Colorectal Screening
You celebrate your 45th birthday. Your primary physician issues a referral for routine colorectal cancer screening.
βScreening at 45 catches and removes polyps before they ever have the chance to become cancerous.β
Midlife Zone 2 Cardio & Strength Regimen
Balancing a demanding executive career, your weekly physical activity has slipped to under 30 minutes.
βCombine 150 minutes of conversational cardio with 2 weekly strength sessions for longevity.β
Biennial Breast Cancer Mammography
At age 40, your health plan sends a reminder for your baseline screening mammogram.
βBiennial mammograms starting at age 40 reduce breast cancer mortality by over 40%.β
Sodium Reduction & Potassium-Rich DASH Diet
Your recent checkup reveals borderline high blood pressure (134/86 mmHg). You look at your dinner meal plan.
βCut processed salt! Eat potassium-rich leafy greens, avocados, berries, and legumes to relax arteries.β
Metabolic Audit & Fasting HbA1c Screening
You notice afternoon energy crashes and a widening waistline. Your doctor offers an HbA1c blood test.
βCatching pre-diabetes early lets you reverse it completely before it harms your eyes, kidneys, and nerves.β
Comprehensive Eye Exam & Intraocular Pressure Audit
You notice mild eye fatigue after work. An optometrist recommends a comprehensive dilated exam with tonometry.
βGlaucoma is the "sneak thief of sight." Routine eye exams save your vision with simple eye drops.β
Age-50 Recombinant Shingles (Zoster) Immunization
Reaching age 50, your pharmacist informs you that chickenpox virus dormant in your spinal ganglia can reactivate as shingles.
βTwo doses of Shingrix protect against months of agonizing shingles nerve pain!β
Bystander Sudden Cardiac Arrest & Hands-Only CPR
While walking in the park, a nearby runner suddenly collapses to the ground, unconscious, unresponsive, and not breathing normally.
βPush hard and fast to the beat of "Stayinβ Alive" (100β120 beats per minute) until the AED arrives!β
Coronary Artery Calcium (CAC) Scan & Risk Stratification
At age 50 with borderline cholesterol, your doctor discusses getting a non-contrast CT Coronary Artery Calcium (CAC) score.
βA coronary calcium scan reveals silent heart disease before a heart attack ever occurs.β
Dermatologic "ABCDE" Mole Audit & Biopsy
You notice a dark pigmented lesion on your shoulder that has asymmetrical jagged borders and multiple shades of brown.
βFollow ABCDE rules (Asymmetry, Border, Color, Diameter >6mm, Evolving) and see a dermatologist immediately.β
Fall Prevention & Tai Chi Balance
You notice throw rugs slipping on polished hardwood floors, and navigating dark hallways at night feels uncertain.
βSecure loose rugs, install motion nightlights, and practice daily single-leg balance exercises.β
Pharmacist Polypharmacy Audit & Hydration
You are taking 7 different daily prescriptions from multiple doctors and occasionally experience morning dizziness.
βBring all medication bottles to your pharmacist every 6 months for a Brown Bag Beers Criteria review.β
Senior Pneumococcal & RSV Respiratory Defense
Entering your 65th year, your physician recommends the PCV20 conjugate pneumococcal vaccine and seasonal RSV immunization.
βPneumococcal conjugate vaccines provide lifelong defense against bacterial pneumonia.β
Cognitive Reserve & Social Neurogenesis
In retirement, you have extra free hours each day. You decide how to spend your mental energy.
βChallenge your brain with novel skills and rich daily social conversations to keep neuroplasticity sharp!β
Bone Density DEXA Scan & Calcium/D3/K2 Protocol
At age 65, your doctor recommends a dual-energy X-ray absorptiometry (DEXA) bone density scan.
βKeep bones strong with weight-bearing exercises, calcium, Vitamin D3, and regular DEXA checks.β
Extreme Summer Heatwave & Electrolyte Safety
A record-breaking summer heatwave pushes indoor temperatures past 98Β°F (37Β°C) with no breeze.
βDrink water before feeling thirsty! Move to air-conditioned spaces during extreme summer heatwaves.β
Audiometric Hearing Loss & Neurocognitive Preservation
You struggle to hear family conversations in crowded rooms and frequently ask people to repeat themselves.
βGet an annual audiogram and wear hearing aids to keep your brain sharp and socially engaged!β
Bathroom Environmental Safety: Wall Grab Bars & Non-Slip Mats
Stepping into a slick tiled bathtub without grab bars or non-slip mats feels unstable.
βInstall professional grab bars inside showers and beside toilets; remove loose throw rugs.β